Since 2005, The Pew Charitable Trusts and its partners have conducted research, provided technical assistance and legislative support to governments, and made strategic grants to advance fiscally sound, data-driven criminal and juvenile justice policies and practices that protect public safety and reduce correctional populations and costs.īuilding on this record, Pew is working with state and local officials and community stakeholders around the country to reform jail, community supervision, and juvenile legal systems by: But decades of research have revealed a range of strategies that are more effective for achieving public safety. doi: 10.1111/1754-9485.Crime and correctional control-any court-ordered supervision of an individual, whether in the community, as with probation or parole, or in a facility, such as a jail or prison-create substantial burdens for governments and taxpayers, as well as for people in confinement or under supervision and their families. Effects of Interruptions of External Beam Radiation Therapy on Outcomes in Patients With Prostate Cancer. The Effect of Overall Treatment Time on Local Control in Patients With Adenocarcinoma of the Prostate Treated With Radiation Therapy. Effects of Prolongation of Overall Treatment Time Due to Unplanned Interruptions During Radiotherapy of Different Tumor Sites and Practical Methods for Compensation. Does Treatment Duration Affect Outcome After Radiotherapy for Prostate Cancer? Int J Radiat Oncol Biol Phys (2008) 72(5):1402–7. doi: 10.1016/j.ctro.2020.10.003ĭ’Ambrosio DJ, Li T, Horwitz EM, Chen DYT, Pollack A, Buyyounouski MK. Treatment Interruptions Affect Biochemical Failure Rates in Prostate Cancer Patients Treated With Proton Beam Therapy: Report From the Multi-Institutional Proton Collaborative Group Registry. Han JE, Chang J, Rosen L, Hartsell W, Tsai H, Chen J, et al. SBRT (stereotactic body radiation therapy) Treatment delay prostate cancer treatment interruption treatment noncompletion.Ĭopyright © 2022 Pepin, Zwart, Danner, Ayoob, Yung, Collins, Kumar, Suy, Aghdam and Collins. The incidence of treatment interruptions in patients undergoing SBRT for their prostate cancer was low. There were no significant sociodemographic, oncologic, or treatment variables that predicted treatment interruption on multivariate analysis. Other reasons included unplanned breaks due to acute side effects (21.2%), logistical issues (18.2%), non-treatment related health issues (9.1%), and inclement weather (3.0%). The most common reason for a delay was a technical issue (48.5%), including the machine maintenance, fiducial misalignment, or inadequate pretreatment bowel preparation. In patients who experienced a delay, nearly half (45.5%) experienced only a one-day delay. Median length of time to complete treatment was 11 days (range 5-155 days). Thirty-three patients experienced a treatment delay. Multivariate analysis was performed via binary logistic regression modeling on PSPP.Īll individuals in the cohort eventually completed the planned 5-fraction regimen. In the patients who experienced delays, chart review was performed to characterize the length and etiology of each delay. Non-completion was defined as patients treated with less than 5 fractions. A treatment delay was defined as a patient requiring longer than 14 days to complete 5 fractions of SBRT. One thousand three hundred and thirty-six patients treated with SBRT from 2008 to 2021 at the Georgetown University Hospital for prostate cancer were included in this retrospective study. This study sought to determine the incidence of treatment delay and characterize the etiology and length in a large cohort of men treated with SBRT for their prostate cancer. Stereotactic body radiation therapy (SBRT) decreases the number of treatments compared to conventionally fractionated radiation hence, it has the potential to decrease treatment delays and non-completion. During the course of radiation treatment for prostate cancer, patients may have unintentional interruptions in their treatment course due to a wide variety of factors.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |